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Mitochondrial superoxide regulates nuclear envelope integrity and ageing via redox-mediated lipid metabolism | Nature Metabolism

The OPLS-DA models exhibited a clear separation between the two groups, and the metabolomic profile of PsA patients was characterized by a significant increase in glucose and glycyl proline, and a significant decrease in alanine, glutamine, methionine, serine and the branched-chain amino acids leucine, isoleucine and valine

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These results support that the topology of the EHL is unique to the entire Lot DUB family and can be considered a standard characteristic of Lots